At what age do symptoms of Huntington's disease typically begin to appear?

Huntington's disease is a neurodegenerative disorder that is characterized by motor dysfunction, cognitive decline, and psychiatric symptoms. The onset of symptoms typically occurs in adulthood, generally around the ages of 30 to 50. This timing is important because it allows for the accumulation of genetic changes over the years before symptomatic expression.

Specifically, symptoms often begin to appear around age 30, as indicated in the correct answer. This age range aligns with the understanding of the genetic basis of the disease, where the CAG repeat in the HTT gene expands over generations. The progressive nature of the symptoms often leads to significant impairment in the later stages of the disease, impacting both individuals and their families.

The other options suggest an earlier age for symptom onset, which does not align with the established medical understanding of Huntington's disease. It is rare for symptoms to manifest in early childhood, adolescence, or even after the age of 60. Therefore, the correct identification of approximately age 30 as the typical onset reflects the general clinical presentation of the condition.