What distinguishes Drug Schedule 1 substances?

Drug Schedule 1 substances are defined by their characteristics of having no accepted medical uses and a high potential for abuse. This classification indicates that these substances are considered to pose significant risks to public health and safety due to their addictive qualities and lack of therapeutic benefits recognized by medical professionals. Examples of Schedule 1 substances include heroin and LSD, which are subject to the strictest regulations under federal law.

The other choices reflect characteristics of different drug schedules or regulatory requirements. Some substances requiring a prescription for every refill is applicable to various controlled substances but does not specifically define Schedule 1 drugs. A classification that includes drugs with low abuse potential would pertain more to Schedule 4 or 5 drugs, which are seen as safer and typically have accepted medical uses. Ordering substances over the phone generally relates to certain schedules but does not pertain to the fundamental distinction of Schedule 1 substances, which is their lack of accepted medical use and high abuse potential.