What is a typical blood sugar (BS) level observed in HHNC coma?

In hyperglycemic hyperosmolar nonketotic coma (HHNC), the blood sugar levels can reach extremely high values, often significantly above normal ranges. Typically, levels can be observed upwards of 600 mg/dl, and in severe cases, they can rise as high as 1000 mg/dl or even beyond. This condition is characterized by a significant increase in blood glucose without the presence of ketoacidosis, leading to a high osmolar state that can impair consciousness and result in coma.

The hyperglycemia in HHNC is often gradual, allowing for elevated blood sugar levels to reach such extremes. This is in contrast to diabetic ketoacidosis (DKA), which usually presents with lower blood sugar levels since it typically ranges from 250 mg/dl to 800 mg/dl. In HHNC, the body's insulin level is often sufficient to prevent ketogenesis, thus differentiating it from DKA while still allowing for dangerously high blood sugar levels.

Understanding that HHNC can present with blood glucose levels approaching 1000 mg/dl is crucial for recognizing the severity of the condition, guiding treatment, and providing the appropriate emergency care needed for patients.