What neurotransmitter is primarily associated with the cholinergic system?

Acetylcholine is the primary neurotransmitter associated with the cholinergic system. This system plays a crucial role in various physiological functions, including muscle movement, memory, and the modulation of the autonomic nervous system. Acetylcholine is released by cholinergic neurons and binds to receptors on target cells, which can be either excitatory or inhibitory depending on the receptor type.

In the context of the autonomic nervous system, acetylcholine is the neurotransmitter responsible for transmitting signals in both the sympathetic and parasympathetic pathways, influencing heart rate, digestion, and other involuntary actions. The presence of acetylcholine and its action at synapses underscores its importance in both peripheral and central nervous system signaling. Understanding this helps clarify the essential role that acetylcholine plays in both health and disease.