Which aspect defines Drug Schedule 2 drugs?

Drug Schedule 2 drugs are classified as substances that have a high potential for abuse and, as a result, are strictly regulated. One key aspect of Schedule 2 drugs is indeed that they require a written prescription for each refill. This regulation is in place to minimize the risk of misuse and to ensure that such medications are only dispensed under close supervision by a healthcare provider.

The requirement for a written prescription aims to prevent unauthorized refills and to promote careful monitoring of the patient's use of the medication. This is particularly important because Schedule 2 drugs can lead to severe psychological or physical dependence. Other classifications of drugs may have different refill procedures; for example, some may allow for telephonic prescriptions or automatic refills, which is not the case for Schedule 2 drugs.

Drugs in this schedule do not fit the criteria of having no potential for abuse, nor can they be repeatedly prescribed without a new prescription. Additionally, they are not available over-the-counter, as this would contradict the tight regulations imposed due to their potential for abuse.